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Sebastian Seung

Princeton Neuroscience Institute

Functionalist What matters is the organisation of the processing, not the material

Sebastian Seung is a computational neuroscientist who moved from physics into neuroscience and now works at Princeton after faculty appointments at MIT. His 2012 book Connectome: How the Brain’s Wiring Makes Us Who We Are, published by Houghton Mifflin Harcourt, made the connectome a public concept and stated the structural identity hypothesis in a form the field now argues with.

The hypothesis holds that the pattern of connections between neurons, including their functional states, is the physical basis of identity and memory. Genes assemble an initial wiring template and experience rewrites it, so the person a brain becomes is the record of everything that modified its wiring. The claim is functionalist in structure. It locates the self in the organization of the processing, rather than in the material, which places Seung with the position this site labels on that basis.

Seung also builds the instruments his hypothesis needs. He launched EyeWire in 2012, a citizen science project that recruited online players to trace retinal neurons, as a test of whether distributed human annotation could scale connectome mapping. This site covers his book’s argument in the structural identity post, where the open problems are stated as well, since a wiring pattern is a description and a person is a running process, and whether pattern preservation implies preserved experience is the question the hypothesis leaves for the emulation program.

Known for. The Connectome book, the structural identity hypothesis, EyeWire

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